Originally Posted by NHPATRIOT
Only if they have the correct fuel lines. Also, the fuel injectors are different for FF vehicles. Unless the vehicle was made to be FF it is not wise to run E85. Period. Can you - yes. Should you - no. You can not tune it to achieve no MPG loss either. Anyone who claims they have is bs'ing folks.
Fuel lines in almost every vehicle since 2000 have been built to be alcohol resistant. As an example 2006 to 2008 f150's can be had with a ffv 5.4 or a non ffv 5.4, the fuel lines are the same, the ffv just has a sensor to figure out the mixture of ethonal to gas. Yes the injectors are different but only because the ffv injectors have to flow about 30% more fuel. Tuned was not the word I wanted, tuning can get you close fuel economy wise but the engine has to be built for it, it has to have higher compression to take advantage of the higher octane. If auto manufacturers would tune their e85 vehicles properly all of them would make more power on e85, but so far ford is the only one who has figured that out, and that was only for a couple years.