I have and yes, most vehicles have gone with this "combo" unit.
If you have a trim tool and are careful, you won't break any of the retainer clips. However, they will be extremely tight and require a bit of force to get them to release. I didn't document the procedure and really can't offer any words of wisdom unfortunately. R&R procedure is pretty much straight forward with very limited room once you get inside the door itself to release the latch/lock rods from the actuator. Highly recommend a small light and a mirror to help you see what is going on near the actuator assembly if you aren't familiar with this type of repair. The latch/lock rods will flex enough, but prefer not to be bent to an extreme.