I don't believe the radio update v13.48 does anything for the HVAC (climate) system...that is a separate TSB (view some of my past posts to get the number).
The radio update DID affect my rear window/mirrors defroster turning on automatically when I would remote start...now it doesn't.
Long story short...
I was having a host of radio issues running v13.19, and my climate system would turn completly off when I would open the driver's door after a remote start.
After a trip to the dealership, two separate TSBs were performed...one to fix the climate system shutting off completly after a remote start (the front window defrost fan still shuts off from "Full" like it did before when I would open the driver's door, but now I don't have to turn the climate system
back on manually), and another to upgrade the radio to 13.48 (which seemed to fix all my radio issues).
My only complaint is the rear window/mirrors defroster no longer comes on automatically after a remote start with the radio upgrade to v13.48.