I own a 2002 Jeep Grand Cherokee Laredo 4.0. The past two years I have been dealing with these same codes, I have done a complete tune up, fuel system clean out, and fuel pump. I took my Jeep to a mechanic to get the fuel system cleaned out and he stated that if that did not work then I would have to replace my fuel pump because the regulator could have gone out. Recently I did that and I am still getting the codes P0300, P0301, P0306. When it starts acting up is when I go over 50 mph for a mile or so, then I have to stop or slow down. Once I come to a stop I put her in park or neutral, and shut her down then restart and the issue goes away until I have to slow down or stop again. I know these codes are Misfire codes. Can someone please help me figure this issue out.